Psychedelic sciences present a worldview of global ecological networking on molecular, psychological, and cultural levels -- a worldview which goes beyond boundaries into dynamic interdependence and into a new definition of the intersubjective self. This presentation dwells in the phenomenology of the psychedelic experience, lifting the lid on the underlying neural correlates to the mystical state, and positions the modern psychedelic renaissance within our timeless cultural romance with psycho-active plants. What do psychedelic experiences illuminate about the nature of consciousness and “self”? Is this truly an “archaic revival”, a remembrance of our relations within the natural world? Is this to be a reboot of Western psychiatry, or a new syncretic shamanic lineage? This presentation summarizes key areas of research including the completed psilocybin clinical trials, and suggests health policy reforms to end the prohibition of psychedelics. The boundaries between body & soul, science & spirit, evidence & policy are all explored for problems and possibilities.